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KMID : 0361719940050040403
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Korean Journal of perinatology
1994 Volume.5 No. 4 p.403 ~ p.409
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Types and Principle Management of Medical High Risk Pregnancy
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Abstract
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This Study was performed to investigate the effects of enteral nutrition on the changes of fasting plasms gastrin concentration and neonatal clincal courses in infants of very-low-birth-weight
Eighteen infants with respiratory distress who received ventilator therapy at St. Mary's Hospital, Catholic University Medical College in 1993 were observed. Nine infants. Who took first milk feeding before the 5th day of life(early feeding
group)
and
nine infants who started enteral feeding after the 10th
day of life(late feeding group) were included. All were appropriate for gestational age and none of them had sepsis or metabolic derangements.
Fasting plasma gastrin levels were measured for peripheral venous blood at 3~5 days, 10~14 days and 28 days after birth. Neonatal clincal course was analysed after reviewing the neonatal intensive care record of each infant.
@ES The results were as follows ;
@EN 1) There was no significant difference of mean plasma gastrin concentration between two groups at 3~5 days of age. Mean plasma gastrin concentration was markedly increased by 10~14 days of age in early feeding group but it was not increased
in
late
feeding group. At 28 days of age, mean plasma gastrin concentration showed continuous increase in early feeding group and there was a catch-up increase of plasma gastrin level after enteral feeding in late feeding group.
2) Early feeding group showed earlier complete enteral feeding, lower incidence of feeding intolerance and shorter duration of parenteral nutrition than late feeding group Lesser degree of maximum weight loss, earlier regaining of birth weight
and
shorter duration of hospitalization were ayailable in early feeding group.
The above results showed that mainteining small amount of enteral nutrition from the first few days of life not only could induce earlier and continuous increase of fasting plasma gastrin level also had beneficial effects of the neonatal clincal
courses
in very-low-birth-weight infants. It could be advisible to start minimal enteral feeding as early as possible unless there were contraindications of enteral feeding.
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